Novartis International AG is a Swiss multinational pharmaceutical company based in Basel, Switzerland, ranking number two in sales (46.806 billion US$) among the world-wide industry in 2010. Novartis manufactures such drugs as clozapine (Clozaril), diclofenac (Voltaren), carbamazepine (Tegretol), valsartan (Diovan) and imatinib mesylate (Gleevec/Glivec). Additional agents include cyclosporin (Neoral/Sandimmun), letrozole (Femara), methylphenidate (Ritalin), terbinafine (Lamisil), and others. Novartis Corporation has what the doctor ordered. As the US headquarters of Switzerland-based Novartis AG, the unit handles administration, sales, and marketing for a vast product line of prescription drugs, vaccines, consumer medicines, and veterinary products. But wait, there's more! Novartis Corporation also oversees the Novartis Institutes for Biomedical Research, which is headquartered in the US, and charged with the job of discovering new medicines to add to the company's ever-expanding pipeline. Novartis Corporation also headlines dozens of other US business units including Novartis Pharmaceuticals Corporation (NPC) and the US locations of Novartis' Alcon ophthalmics and Sandoz generics businesses. Novartis was created in 1996 from the merger of Ciba-Geigy and Sandoz Laboratories, both Swiss companies with long histories. Ciba-Geigy was formed in 1970 by the merger of J. R. Geigy Ltd (founded in Basel in 1758) and CIBA (founded in Basel in 1859). Combining the histories of the merger partners, the company's effective history spans 250 years.